Michael Graziano, the filmmaker behind Resistance, a ground-breaking new film on the growing threat of antibiotic-resistant bacteria, took time to answer some of our burning questions. Like many of us, Graziano isn’t a scientist or a doctor, but decided that this was a story the public urgently needed to hear. Keep reading to learn more about his experience making the film and what you can do to help curb antibiotic resistance.
Q: What made you decide to tackle the problem of antibiotic resistance?
A: Our previous film Lunch Line was about the history and politics of the National School Lunch Program. In the process of making and touring that film we learned a lot about public health and became acquainted with a number of agriculture and public health advocacy groups. Through that work we started hearing about MRSA (resistant staph) infections in school locker rooms, day care centers and the like. At the same time we also started hearing about the overuse of antibiotics on farms. I decided to look more into the issue and was shocked by what I learned. I thought the problem deserved a closer, and more generally accessible examination than I could find at the time.
Q: What was the biggest or most surprising thing you learned in the process of making the film?
A: There are a few. One is that there are basically no new antibiotics in the pharmaceutical pipeline, and even if a new compound were discovered today it could easily take 10 years and $1 billion for that compound to become a clinically useful medicine. To make matters worse, the large investment in time and money required for antibiotic development, along with some other factors addressed in the film, has caused many pharma companies to shutter their antibiotic development units so there are now only a small handful of companies actually doing this critical research. Read the full article…